Study Says a High-fat Diet Stops the Brain From Telling You When You Are Full

Listening to your head is not always the answer when it comes to deciding whether or not to go back for second helpings.

A high-fat diet has been linked with turning off the signal in the brain that indicates when you are full.

The study published in the Journal of Clinical Investigation suggests a previously unknown gut-brain connection that helps explain how extra servings lead to weight gain.

Corresponding author Dr Makoto Fukuda, assistant professor of paediatrics at Baylor College of Medicine, said: “We have uncovered a new piece of the complex puzzle of how the body manages energy balance and affects weight.”

Researchers found that mice consuming a high-fat diet showed increased levels of gastric inhibitory polypeptide (GIP).

This hormone is produced in the gut and is involved in managing the body’s energy balance.

In the study, scientists found that excess GIP travels through the blood to the brain, where it inhibits the action of leptin – the satiety hormone.

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SOURCE: Breaking